Trial guide
Dog longevity clinical trials: LOY-002 STAY, rapamycin TRIAD, and eligibility
Compare major canine longevity studies, learn what enrollment means, and verify trial eligibility, placebo design, costs, locations, and informed consent.
Direct answer
Two prominent canine longevity research programs are Loyal's STAY study for LOY-002 and the Dog Aging Project's TRIAD study of rapamycin. They test different interventions under different protocols. A public trial listing is not proof of current enrollment, eligibility, benefit, or approval.
STAY and TRIAD are not interchangeable
STAY is the sponsor's large, multi-site study associated with LOY-002, a daily pill developed for senior dogs. TRIAD is a Dog Aging Project study of rapamycin. Each has its own eligibility criteria, endpoints, visits, locations, and oversight.
Combining their headlines into a generic claim that 'dog anti-aging pills work' would be scientifically invalid. Results must remain attached to the exact intervention and population studied.
What trial participation usually involves
A credible study provides informed consent, eligibility screening, a protocol, study visits, potential risks, contact information, privacy terms, and a method for reporting adverse events. Randomized trials may assign a placebo, so participation does not guarantee active treatment.
Owners should ask which expenses the study covers, what happens if the dog becomes ill, whether the regular veterinarian remains involved, and how incidental findings are handled.
Eligibility is more than breed and age
Trials may screen weight, age, health history, current diagnoses, medication use, geography, availability for visits, laboratory results, and expected ability to complete follow-up. Public summaries often omit details that appear in the consent and protocol.
Never alter a dog's medication or health record to qualify. Exclusion criteria protect the dog and the validity of the study.
How this site verifies listings
We link to the sponsor or research operator, record a last-checked date, avoid calling a site 'enrolling' without current source support, and remove stale listings from indexable pages. Owners must still confirm status directly before traveling or sharing medical information.
Future trial data should include a dated change log so readers can see when a site opened, paused, completed enrollment, or posted results.
Each listing should identify the intervention, sponsor, study phase or design, recruitment status, last verification date, geographic site, official contact route, and source URL. We will not infer enrollment from an old press release or a clinic's general research page. If current status cannot be confirmed, the listing should say unknown rather than enrolling.
A correction history should retain the prior status, new status, evidence URL, and verification timestamp. This creates a reusable dataset for owners, journalists, and researchers while preventing stale enrollment pages from becoming search-engine traps.
Frequently asked questions
Will my dog receive the active drug?
Not necessarily. Randomized controlled trials may use placebo assignment, which should be explained during consent.
Does joining a trial cost money?
Coverage and owner expenses vary by protocol. Confirm examinations, travel, medications, emergency care, and compensation in writing.
Where can I check enrollment?
Use the current sponsor or research-operator page and contact the listed study team. Third-party summaries can become stale.
Primary sources and limitations
Supports: Current sponsor information about the STAY study, its design, sites, and participation questions.
Limit: Trial enrollment and eligibility must be confirmed directly with the study sponsor or participating clinic.
Supports: Independent research-program description for a placebo-controlled study of rapamycin and healthy aging in companion dogs.
Limit: A research study is not approval for owners to give rapamycin to dogs outside veterinary and study oversight.
Supports: Sponsor-reported intended populations, dosage form, development status, and the three major technical requirements described for LOY-002.
Limit: This is the developer's own product page, not independent confirmation of lifespan extension or an FDA approval listing.
Continue the evidence trail
Educational information only. This page does not diagnose, prescribe, or replace a veterinarian who knows your dog.