{"name":"LOY-002 public regulatory milestone timeline","canonicalUrl":"https://doglongevityinfo.com/data/loy-002-timeline","license":"https://creativecommons.org/licenses/by/4.0/","publisher":"Canine Longevity Atlas","reviewedAt":"2026-07-31","methodology":"https://doglongevityinfo.com/about/methodology","limitations":"Sponsor-reported milestones remain classified as sponsor-reported until a product-specific regulator record independently confirms them. Technical-section acceptance is not approval.","records":[{"date":"2025-02-26","event":"Reasonable expectation of effectiveness milestone reported","status":"Sponsor-reported FDA technical-section acceptance","source":"https://loyal.com/posts/loy-002-receives-rxe-from-the-fda"},{"date":"2025-12-01","event":"Target Animal Safety technical section accepted","status":"Sponsor reports acceptance occurred in December 2025","source":"https://loyal.com/posts/loy-002-tas"},{"date":"2026-01-13","event":"Safety milestone explainer published","status":"Sponsor update; approval still described as pending","source":"https://loyal.com/posts/loy-002-tas"},{"date":"2026-07-31","event":"Atlas primary-source review","status":"Two of three major requirements shown complete; conditional approval not confirmed","source":"https://loyal.com/for-dog-owners"}]}